哲学博士，1985年12月生，副教授
硕士生导师 (化学学硕 + 材料与化工专硕）
专 业： 化学
研究领域： 有机小分子荧光探针及生物成像/光动力治疗
办 公 室和实验室： 理北501，生化楼624
电子邮件：swj114@gzhu.edu.cn
教育经历
2009.08–2013.07，香港中文大学，化学系，哲学博士学位。导师：Prof. Dennis K. P. Ng
2005.09–2009.07，中国科学技术大学，化学物理系，理学学士学位。导师：张广照 教授
工作经历
2016.01–今，威斯尼斯wns888官方网站，威斯尼斯wns888官方网站，讲师，副教授
2013.08–2015.12，香港中文大学，化学系，博士后研究员。合作导师：Prof. Dennis K. P. Ng
讲授课程和指导学生项目
本科生课程：有机化学、有机化学实验.
指导学生项目和获奖：指导学生获得本科毕业论文（设计）“创新”一等奖，广东省“攀登计划”重点项目立项2次，省级“创新”项目立项1次。
研究方向
氟硼二吡咯 (BODIPY)，荧光探针(Fluorescent probes),功能有机染料 (Organic dyes), 聚集诱导发光(AIE)，生物成像(Bioimaging)
承担项目
[1] 国家自然科学基金青年项目，主持，2021.01-2023.12
[2] 广东省自然科学基金项目，主持，2018.05-2021.04
[3] 广州市基础研究计划市校（院）联合资助项目，主持，2021.05-2023.04.
[4] 广东省教育厅高等教育创新强校工程-青年创新项目，主持，2017.04-2019.03
[5] 广州市教育局市属高校科研项目-青年项目，主持，2017.01-2018.12
[6] 威斯尼斯wns888官方网站启动项目，主持，2016.01–2017.12
[7] 威斯尼斯wns888官方网站新苗计划，主持，2016.01–2017.12
代表性研究成果（仅为一作和/或通讯作者）
[1] Wen-Jing Shi, Xu-Hui Yan, Jinrong Yang, Yong-Feng Wei, Yi-Tong Huo, Cai-Ling Su, Jin-wu Yan*, Dongxue Han, and Li Niu*, Development of meso-Five-Membered Heterocycle BODIPY-Based AIE Fluorescent Probes for Dual-Organelle Viscosity Imaging, Anal. Chem. 2023, 95(25), 9646-9653. (获邀在“分析人”报道)
[2] Wen-Jing Shi*, Ru Chen, Jinrong Yang, Yong-Feng Wei, Yuhui Guo, Zi-Zhou Wang, Jin-wu Yan*, Li Niu, Novel Meso-Benzothiazole-Substituted BODIPY-Based AIE Fluorescent Rotor for Imaging Lysosomal Viscosity and Monitoring Autophagy, Anal. Chem. 2022, 94(42), 14707-14715. (获邀在“分析人”报道)
[3] Wen-Jing Shi*, Yong-Feng Wei, Jinrong Yang, Hui-Zhi Li, Qing-Hui Wan, Yuxuan Wang, Huaxiang Leng, Kun Chen, Jin-wu Yan*, Novel Meso-trifluoromethyl BODIPY-based Near-infrared-emitting Fluorescent Probes for Organelle-specific Imaging of Cellular Viscosity, Sensors Actuat. B Chem 2022, 359, 131594.
[4] Wen-Jing Shi*1, Jinrong Yang1, Yong-Feng Wei, Xiao-Tong Li, Xu-Hui Yan, Yuxuan Wang, Hua-xiang Leng, Liyao Zheng, Jin-Wu Yan*, Novel Cationic Meso-CF3BODIPY-based AIE Fluorescent Rotors for Imaging Viscosity in Mitochondria, Chem. Commun. 2022, 58, 1930-1933.
[5] Wen-Jing Shi*, Qing-Hui Wan, Fen Yang, Xuan Wang, Yong-Feng Wei, Xin-Ru Lin, Jian-Ying Zhang, Ri-Hui Deng, Jie-Yan Chen, Liyao Zheng, Fenggang Liu, Liqian Gao*, A Novel TCF-aza-BODIPY-based Near-infrared Fluorescent Probe for Highly Selective Detection of Hypochlorous Acid in Living Cells, Spectrochim. Acta A2022, 279, 121490.
[6] Yuhui Guo1, Huaxiang Leng1, Yuxuan Wang,Wen-Jing Shi*, Lei Zhang*, Jinwu Yan*, A Novel H2O2-activated NIR Fluorescent Probe for Imaging β-amyloid Fibrils and Mitochondrial Viscosity, Dyes Pigments 2022, 206, 110665.
[7] Yuxuan Wang, Jinrong Yang, Qingxiu Chen, Junyi Su, Wen-Jing Shi*, Lei Zhang, Chunli Xia*, Jinwu Yan*, Rotor-Tuning Boron Dipyrromethenes for Dual-Functional Imaging of Aβ Oligomers and Viscosity, ACS Appl. Bio Mater. 2022, 5(6), 3049-3056.
[8] Yong-Feng Wei1, Xuan Wang1, Wen-Jing Shi*, Ru Chen, Liyao Zheng, Zi-Zhou Wang, Kun Chen, Liqian Gao*, A Novel Methylenemalononitrile-BODIPY-based Fluorescent Probe for Highly Selective Detection of Hydrogen Peroxide in Living Cells, Eur. J. Med. Chem.2021, 226, 113828. (获邀在CBG“人物与科研”报道)
[9] Wen-Jing Shi*, Liu-Xia Feng, Xuan Wang, Yan Huang, Yong-Feng Wei, Huai-Jin Ma, Wei Wang, Menghua Xiang, Liqian Gao*, A Near-infrared-emission Aza-BODIPY-based Fluorescent Probe for Fast, Selective, and “Turn-on” Detection of HClO/ClO-, Talanta 2021,233, 122581.
[10] Wen-Jing Shi*, Yong-Feng Wei, Chun-Feng Li, Han Sun, Liu-Xia Feng, Shi Pang, Fenggang Liu*, Liyao Zheng, Jin-Wu Yan*, A Novel Near-Infrared-Emitting Aza-Boron-Dipyrromethene-Based Remarkable Fluorescent Probe for Hg2+in Living Cells, Spectrochim. Acta A 2021,248, 119207.
[11] Yan Huang, Chun-Feng Li, Wen-Jing Shi*, Hui-Ya Tan, Zhi-Zhou He, Liyao Zheng, Fenggang Liu, Jin-Wu Yan*, A Near-Infrared BODIPY-Based Fluorescent Probe for Ratiometric and Discriminative Detection of Hg2+ and Cu2+Ions in Living Cells. Talanta 2019,198, 390-397.
[12]Wen-Jing Shi, Chun-Feng Li, Yan Huang, Hui-ya Tan, Yong-Feng Wei, Fenggang Liu*, Liu-Xia Feng, Liyao Zheng, Guo-Shu Chen, Jin-wu Yan*, A BODIPY-based “OFF-ON” Fluorescent Probe for Fast and Selective Detection of Hypochlorite in Living Cells,Dyes Pigments2019, 170, 107566.
[13] Wen-Jing Shi*, Yan Huang, Wancui Liu, Dan Xu, Shu-Ting Chen, Fenggang Liu*, Liyao Zheng, Kun Chen*, A Remarkable Colorimetric Probe for Fluorescent Ratiometric and ON-OFF Discriminative Detection of Hg2+and Cu2+ by Double-Channel Imaging in Living Cells,Dyes Pigments2019, 171, 107782.
[14] Wen-Jing Shi, Jian-Yong Liu, Pui-Chi Lo, Dennis K. P. Ng*, Selective Detection of Hg2+Ion with Boron Dipyrromethene-Based Fluorescent Probes Appended with a Bis(1,2,3-triazole)amino Receptor.Chem. Asian J. 2019, 14(7), 1059-1065.
[15] Wen-Jing Shi, Dennis K. P. Ng*, Shirui Zhao, Pui-Chi Lo*, A Phthalocyanine‐Based Glutathione‐Activated Photosensitizer with a Ferrocenyl Boron Dipyrromethene Dark Quencher for Photodynamic Therapy,ChemPhotoChem 2019, 3(10), 1004-1013.
[16]Wen-Jing Shi*, Pui-Chi Lo*, Dennis K. P. Ng*, Synthesis and Acid-Responsive Spectral Properties of Near-Infrared-Absorbing Donor-π-Donor-type Aza Boron Dipyrromethenes. Dyes Pigments 2018, 154, 314-319.
[17]Wen-Jing Shi, Takumi Kinoshita*, Dennis K. P. Ng*, Ethynyl-Linked Donor-π-Acceptor Boron Dipyrromethenes for Panchromatic Dye-Sensitized Solar Cells, Asian J. Org. Chem. 2017,6(6), 758-767.
[18]Wen-Jing Shi, Takumi Kinoshita*, Dennis K. P. Ng*, Push–Pull Distyryl Boron Dipyrromethenes as Near‐Infrared Sensitizers for Dye‐Sensitized Solar Cells,Asian J. Org. Chem. 2017, 6(10), 1476-1485.
[19]Wen-Jing Shi, Pui-Chi Lo*, Shirui Zhao, Roy C. H. Wong, Qiong Wang, Wing-Ping Fong, Dennis K. P. Ng*, A Biotin-Conjugated Glutathione-Responsive FRET-Based Fluorescent Probe with a Ferrocenyl BODIPY as the Dark Quencher. Dalton Trans. 2016, 45, 17798-17806.
[20] Wen-Jing Shi, Roel Menting, Eugeny A. Ermilov, Pui-Chi Lo, Beate Röder, Dennis K. P. Ng*, Formation and Photoinduced Processes of the Host-Guest Complexes of a b-Cyclodextrin-Conjugated Aza-BODIPY and Tetrasulfonated Porphyrins. Chem. Commun. 2013, 49, 5277-5279.
[21] Wen-Jing Shi1, Mohamed E. El-Khouly*,1, Kei Ohkubo1, Shunicih Fukuzumi*, Dennis K. P. Ng*, Photosynthetic Antenna-Reaction-Center Mimicry with a Covalently Linked Monostyryl-Boron Dipyrromethene-Aza-Boron-Dipyrrolmethene-C60 Triad. Chem. Eur. J.2013, 19, 11332-11341.
科研主页
https://www.researchgate.net/profile/Wen-Jing-Shi （Research gate）
团队主页
http://caas.gzhu.edu.cn/index.htm
